Journal article
Compound Heterozygosity for two Genotypes of α-Thalassemia-2 : Hematological, Biosynthetic and DNA Studies
Abstract
Hemoglobin and DNA gene analyses were carried out in two Black Canadian families. In Family Q, both the parents and the brother were found to be heterozygotes for alpha-thalassemia-2 with the following alpha-genotypes: -alpha 3.7/alpha alpha, -alpha 4.2/alpha alpha and -alpha 4.2/alpha alpha, respectively. In Family C, the mother was found to be a homozygote for alpha-thalassemia-2 with the alpha-genotype of -alpha 3.7/-alpha 3.7. In both …
Authors
Wong SC; Chang LS; Olivieri NF; Poon AO; Ali MAM; Groves DJ
Journal
Hemoglobin, Vol. 9, No. 2, pp. 111–126
Publisher
Taylor & Francis
Publication Date
January 1985
DOI
10.3109/03630268508996994
ISSN
0363-0269