Journal article
Altered hippocampal function with preserved cognitive performance in treatment-naive major depressive disorder
Abstract
The hippocampus is implicated in the pathophysiology of major depressive disorder (MDD), with evidence that morphological changes occur with disease progression. It was hypothesized that treatment-naive patients with depression would show performance deficits in hippocampus-dependent memory trials, with concurrent hippocampal activation deficits on functional magnetic resonance imaging, compared with control participants. Thirteen …
Authors
Alders GL; Milne AMB; Minuzzi L; Frey BN; MacQueen GM; Hall GB
Journal
Neuroreport, Vol. 30, No. 1, pp. 46–52
Publisher
Wolters Kluwer
Publication Date
January 2, 2019
DOI
10.1097/wnr.0000000000001163
ISSN
0959-4965