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Feasibility and safety of delivering full‐dose...

Journal article

Feasibility and safety of delivering full‐dose anticoagulation therapy in children treated according to Dana‐Farber Cancer Institute acute lymphoblastic leukemia consortium therapy protocols

Abstract

AbstractBackgroundThe literature is void of an evidence‐based anticoagulation therapy (ACT) management strategy in the context of thrombocytopenia. We examined the impact of thrombocytopenia on low‐molecular‐weight heparin (LMWH) dosing and incidence of bleeding in children with acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LL) who developed thromboembolism (TE) during therapy according to DFCI ALL protocols.ProcedurePatient …

Authors

Bhatt MD; Parmar N; Fowler J; Chan AKC; Athale UH

Journal

Pediatric Blood & Cancer, Vol. 66, No. 2,

Publisher

Wiley

Publication Date

February 2019

DOI

10.1002/pbc.27483

ISSN

1545-5009

Associated Experts

Anthony Chan

Professor, Faculty of Health Sciences

Mihir Bhatt

Associate Professor, Faculty of Health Sciences

Uma Athale

Professor, Faculty of Health Sciences

Labels

Medical Subject Headings (MeSH)

Adolescent Anticoagulants Antineoplastic Agents Child Child, Preschool Cohort Studies Feasibility Studies Female Hemorrhage Heparin, Low-Molecular-Weight Humans Incidence Male Precursor Cell Lymphoblastic Leukemia-Lymphoma Retrospective Studies Thrombocytopenia Thromboembolism

Fields of Research (FoR)

3211 Oncology and carcinogenesis 3213 Paediatrics

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