Journal article
Actions of the muscle relaxant chandonium iodide on guinea-pig ileum and vas deferens preparations
Abstract
The effects of the newly synthesized neuromuscular blocking agent, chandonium iodide (17a-methyl-3beta-pyrrolidino-17a-aza-D-homo-5-androstene dimethiodide) have been investigated on guinea-pig isolated ileum and vas deferens preparations. On the ileum, chandonium (0-1-10-0 mug ml(-1); 1-6 X 10(-7) M-1-6 X 10(-5) M) had weak muscarinic receptor blocking action (pA2 is 5-7), but no antihistamine properties at the concentration tested. No …
Authors
Harvey AL; Paul D; Rodger IW; Singh H
Journal
Journal of Pharmacy and Pharmacology, Vol. 28, No. 8, pp. 617–619
Publisher
Oxford University Press (OUP)
Publication Date
August 1, 1976
DOI
10.1111/j.2042-7158.1976.tb02812.x
ISSN
0022-3573