P053 DP donor specific antibodies pre-renal transplant: Mean fluorescence intensity and epitope pattern alone is not predictive of crossmatch result or clinical outcome

The clinical significance of HLA-DP donor specific antibodies (DSA) detected with solid phase assays in recipients of renal transplants remains poorly defined. Recent literature has elucidated that many patients have a HLA-DP antibody pattern of reactivity against broad cross-reactive epitopes which may be more clinically significant. Typically, a DSA that reacts at a mean fluorescence intensity (MFI) of greater than 5000 results in positive …