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Pregabalin and heart failure: A population‐based...
Journal article

Pregabalin and heart failure: A population‐based study

Abstract

PURPOSE: The anticonvulsant pregabalin is increasingly prescribed for pain, seizures, and psychiatric disorders. Although evidence suggests pregabalin can cause edema and heart failure, its cardiac safety profile in clinical practice is unknown. We sought to examine the risk of heart failure among older patients receiving pregabalin compared to those receiving gabapentin. METHODS: We conducted a population-based cohort study of Ontarians aged …

Authors

Ho JM; Macdonald EM; Luo J; Gomes T; Antoniou T; Mamdani MM; Juurlink DN

Journal

Pharmacoepidemiology and Drug Safety, Vol. 26, No. 9, pp. 1087–1092

Publisher

Wiley

Publication Date

September 2017

DOI

10.1002/pds.4239

ISSN

1053-8569