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Regional Brain Activation in Response to Rectal...
Journal article

Regional Brain Activation in Response to Rectal Distension in Patients with Irritable Bowel Syndrome and the Effect of a History of Abuse

Abstract

Previous studies have demonstrated alterations in brain response to rectal distension in patients with irritable bowel syndrome (IBS) compared to controls. Our aim was to compare regional brain activity in response to rectal balloon distension in patients with IBS and healthy controls. We studied six patients with IBS and six healthy controls. Positron emission tomography scans were obtained during rectal balloon distensions. Statistical …

Authors

Ringel Y; Drossman DA; Turkington TG; Bradshaw B; Hawk TC; Bangdiwala S; Coleman RE; Whitehead WE

Journal

Digestive Diseases and Sciences, Vol. 48, No. 9, pp. 1774–1781

Publisher

Springer Nature

Publication Date

September 2003

DOI

10.1023/a:1025455330704

ISSN

0163-2116