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Quantitative measurements of regional cerebral...
Journal article

Quantitative measurements of regional cerebral blood volume using MRI in rats: Effects of arterial carbon dioxide tension and mannitol

Abstract

A three-dimensional (3D) T1-weighted sequence was used to acquire high spatial resolution whole brain images in rats before and after the injection of an intravascular contrast agent. These T1-weighted images were used to estimate regional cerebral blood volume (rCBV) as a percentage of blood volume in each voxel. Ventilation was manipulated to investigate the effects of altered arterial carbon dioxide tension (PaCO2) on rCBV. In addition, …

Authors

Lin W; Paczynski RP; Kuppusamy K; Hsu CY; Haacke EM

Journal

Magnetic Resonance in Medicine, Vol. 38, No. 3, pp. 420–428

Publisher

Wiley

Publication Date

September 1997

DOI

10.1002/mrm.1910380311

ISSN

0740-3194