Macrolide antibiotics and the risk of ventricular arrhythmia in older adults

Abstract

BACKGROUND: Many respiratory tract infections are treated with macrolide antibiotics. Regulatory agencies warn that these antibiotics increase the risk of ventricular arrhythmia. We examined the 30-day risk of ventricular arrhythmia and all-cause mortality associated with macrolide antibiotics relative to nonmacrolide antibiotics. METHODS: We conducted a population-based retrospective cohort study involving older adults (age > 65 yr) with a new …

Authors

Trac MH; McArthur E; Jandoc R; Dixon SN; Nash DM; Hackam DG; Garg AX

Journal

Canadian Medical Association Journal, Vol. 188, No. 7, pp. e120–e129

Publisher

Joule

Publication Date

April 19, 2016

DOI

10.1503/cmaj.150901

ISSN

0820-3946

Associated Experts

Amit Garg

Assistant Professor (Part-Time), Faculty of Health Sciences

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