Journal article
Metronidazole improves intestinal microcirculation in septic rats independently of bacterial burden
Abstract
To explore the effects of metronidazole (Me) on intestinal microcirculation in septic rats, intravital microscopy (IVM) following 16 hours of colon ascendens stent peritonitis (CASP model) was used. Four groups of animals were studied: control group (sham operation) and CASP group, each with and without Me treatment (10 mg/kg i.v.). In order to investigate the substance-specific effects of Me independently of the antibacterial effects within a …
Authors
Lehmann C; Bac VH; Pavlovic D; Lustig M; Maier S; Feyerherd F; Usichenko T-I; Meissner K; Haase H; Jünger M
Journal
Clinical Hemorheology and Microcirculation, Vol. 34, No. 3, pp. 427–438
Publication Date
2006
DOI
10.3233/chm-2006-865
ISSN
1386-0291