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The use of poly(ethylene oxide) for the efficient...
Journal article

The use of poly(ethylene oxide) for the efficient stabilization of entrapped α-chymotrypsin in silicone elastomers: A chemometric study

Abstract

The enzyme alpha-chymotrypsin, a model for catalytic proteins, was entrapped in different silicone elastomers that were formed via the condensation-cure room temperature vulcanization (CC-RTV) of silanol terminated poly(dimethylsiloxane) with tetraethyl orthosilicate as a crosslinker, in the presence of different poly(ethylene oxide) oligomers that were functionalized with triethoxysilyl groups. The effects of various chemical factors on both …

Authors

Ragheb AM; Hileman OE; Brook M

Journal

Biomaterials, Vol. 26, No. 34, pp. 6973–6983

Publisher

Elsevier

Publication Date

12 2005

DOI

10.1016/j.biomaterials.2005.05.016

ISSN

0142-9612