Journal article
T-cell receptor gene rearrangement in B-Cell non-hodgkin's lymphoma: Correlation with methylation and expression
Abstract
Two of 19 B-cell non-Hodgkin's lymphoma (NHL) were found to have clonally rearranged T-cell receptor (TCR) beta chain genes with a germline TCR-gamma gene configuration. The inappropriate rearrangements had a similar structure to the TCR-beta rearrangements described in B-cell chronic lymphocytic leukemia. All cases analysed displayed a consistent germline transcription of TCR-beta and alpha chain genes which was independent of rearrangement. …
Authors
Leber BF; Amlot P; Hoffbrand AV; Norton JD
Journal
Leukemia Research, Vol. 13, No. 6, pp. 473–481
Publisher
Elsevier
Publication Date
January 1989
DOI
10.1016/0145-2126(89)90169-0
ISSN
0145-2126