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Dieldrin promotes resistance to anoikis in breast...
Journal article

Dieldrin promotes resistance to anoikis in breast cancer cells in vitro

Abstract

Epidemiological evidence suggests that exposure to the pesticide dieldrin, is associated with increased risk of breast cancer and mortality. We hypothesize that dieldrin promotes breast cancer by increasing survival of breast cancer cells. The aims of this study were to measure the effect of dieldrin on survival of breast cancer cells and the expression of tyrosine kinase B (TrkB), a suppressor of anoikis (apoptosis triggered by inappropriate …

Authors

Cameron HL; Foster WG

Journal

Reproductive Toxicology, Vol. 25, No. 2, pp. 256–262

Publisher

Elsevier

Publication Date

February 2008

DOI

10.1016/j.reprotox.2007.11.013

ISSN

0890-6238