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Core outcome set for gene therapy in haemophilia:...
Journal article

Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project

Abstract

BACKGROUND: Gene therapy trial results show potential to cure haemophilia A and haemophilia B. Securing broad access to a cure for a lifelong chronic disease is anticipated to face barriers at the individual and healthcare system levels, which can be partly mitigated by harmonized planning of clinical research studies. The aim of the coreHEM project was to determine the set of outcome measures required to evaluate efficacy, safety, comparative …

Authors

Iorio A; Skinner MW; Clearfield E; Messner D; Pierce GF; Witkop M; Tunis S; panel TC

Journal

Haemophilia, Vol. 24, No. 4, pp. e167–e172

Publisher

Wiley

Publication Date

7 2018

DOI

10.1111/hae.13504

ISSN

1351-8216