Journal article
Plasmin-Mediated Proteolysis of Vascular Endothelial Cell Heparin Releasable Tissue Factor Pathway Inhibitor
Abstract
Background: Fibrinolytic therapy represents a widely available and effective treatment modality for ST segment elevation myocardial infarction (MI). Its overall benefit is attenuated by a high incidence of coronary arterial reocclusion.Methods/Results: Human umbilical vein endothelial cells (HUVEC) were incubated with unfractionated heparin (1.5 U/ml) (to provoke tissue factor pathway inhibitor [TFPI] release) followed by the addition of …
Authors
Li YF; Spencer FA; Becker RC
Journal
Journal of Thrombosis and Thrombolysis, Vol. 15, No. 1, pp. 19–23
Publisher
Springer Nature
Publication Date
2 2003
DOI
10.1023/a:1026136216869
ISSN
0929-5305