Developmental and lactational exposure to environmentally relevant concentrations of dieldrin does not alter pregnancy outcome and mammary gland morphology in BALB/c mice

The objectives of this study were to: (1) determine the dosing range necessary to produce serum levels of dieldrin in mice representative of human body burdens; and (2) define the effect of developmental exposure to environmentally relevant concentrations of dieldrin on mammary gland development. Sexually mature female BALB/c mice (n=140) were randomly assigned to receive vehicle, 0.45, 2.25, 4.5, and 22.5 microg dieldrin/g body weight …