Journal article
Effect of in utero and lactational nicotine exposure on the male reproductive tract in peripubertal and adult rats
Abstract
The objective of this study was to determine the effect of in utero and lactational exposure to nicotine on the male reproductive tract. Dams were randomly assigned to receive saline or nicotine bitartrate (1mg/kg-d s.c.) daily for two weeks prior to mating until weaning (postnatal day 21). Male offspring were sacrificed at 7 (peri-pubertal) and 26 (adult) weeks of age. Nicotine-exposure resulted in retention of spermatids after stage VIII, …
Authors
Lagunov A; Anzar M; Sadeu JC; Khan MIR; Bruin JE; Woynillowicz AK; Buhr M; Holloway AC; Foster WG
Journal
Reproductive Toxicology, Vol. 31, No. 4, pp. 418–423
Publisher
Elsevier
Publication Date
5 2011
DOI
10.1016/j.reprotox.2010.12.004
ISSN
0890-6238