Journal article
Calcium-Dependent Cysteine Protease Activity in the Sera of Patients With Thrombotic Thrombocytopenic Purpura
Abstract
Abstract
Plasma and serum from patients with thrombotic thrombocytopenic purpura (TTP) can cause activation and aggregation of normal human platelets in vitro. It is possible that this platelet-activating factor contributes to the disease. In this report we describe studies designed to identify the platelet-activating factor in TTP. Platelet activation by sera from 15 patients with TTP was inhibited by leupeptin, …
Authors
Murphy WG; Moore JC; Kelton JG
Journal
Blood, Vol. 70, No. 5, pp. 1683–1687
Publisher
American Society of Hematology
Publication Date
November 1, 1987
DOI
10.1182/blood.v70.5.1683.1683
ISSN
0006-4971