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IL-9+ IL-10+ T cells link immediate allergic...
Journal article

IL-9+ IL-10+ T cells link immediate allergic response to late phase reaction

Abstract

The mechanism underlying late-phase allergic reactions (LPR) remains incompletely understood. This study aimed to investigate the role of a newly described subset of T cells, interleukin (IL)-9(+) IL-10(+) T cells, in the pathogenesis of LPR. Using a T helper type 2 (Th2) inflammatory mouse model, we examined the frequency of IL-9(+) IL-10(+) T cells in the jejunum by immunohistochemistry. The LPR in the jejunum was observed afterwards. The …

Authors

He S-H; Liu Z-Q; Chen X; Song C-H; Zhou L-F; Ma W-J; Cheng L; Du Y; Tang S-G; Yang P-C

Journal

Clinical & Experimental Immunology, Vol. 165, No. 1, pp. 29–37

Publisher

Oxford University Press (OUP)

Publication Date

June 2, 2011

DOI

10.1111/j.1365-2249.2011.04394.x

ISSN

0009-9104