Journal article
Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA
Abstract
BACKGROUND: Biomarker-guided clinical trials are increasingly common in metastatic urothelial carcinoma (mUC), yet patients for whom contemporary tumor tissue is not available are not eligible. Technological advancements in sequencing have made cell-free circulating DNA (cfDNA) next-generation sequencing (NGS) readily available in the clinic. The objective of the current study was to determine whether the genomic profile of mUC detected by NGS …
Authors
Agarwal N; Pal SK; Hahn AW; Nussenzveig RH; Pond GR; Gupta SV; Wang J; Bilen MA; Naik G; Ghatalia P
Journal
Cancer, Vol. 124, No. 10, pp. 2115–2124
Publisher
Wiley
Publication Date
May 15, 2018
DOI
10.1002/cncr.31314
ISSN
1097-0142