Journal article
Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis
Abstract
BACKGROUND: Gastro-oesophageal reflux disease is a potential risk factor for the development and progression of idiopathic pulmonary fibrosis (IPF). We aimed to investigate the effect of antacid therapy on disease progression in patients randomly assigned to placebo through analysis of three large, phase 3 trials of pirfenidone in IPF.
METHODS: Patients with IPF from the placebo groups of three trials of pirfenidone (CAPACITY 004, CAPACITY 006, …
Authors
Kreuter M; Wuyts W; Renzoni E; Koschel D; Maher TM; Kolb M; Weycker D; Spagnolo P; Kirchgaessler K-U; Herth FJF
Journal
The Lancet Respiratory Medicine, Vol. 4, No. 5, pp. 381–389
Publisher
Elsevier
Publication Date
5 2016
DOI
10.1016/s2213-2600(16)00067-9
ISSN
2213-2600