Journal article
Serum osteoprotegerin levels and mammographic density among high-risk women
Abstract
PurposeMammographic density is a risk factor for breast cancer but the mechanism behind this association is unclear. The receptor activator of nuclear factor κB (RANK)/RANK ligand (RANKL) pathway has been implicated in the development of breast cancer. Given the role of RANK signaling in mammary epithelial cell proliferation, we hypothesized this pathway may also be associated with mammographic density. Osteoprotegerin (OPG), a decoy receptor …
Authors
Moran O; Zaman T; Eisen A; Demsky R; Blackmore K; Knight JA; Elser C; Ginsburg O; Zbuk K; Yaffe M
Journal
Cancer Causes & Control, Vol. 29, No. 6, pp. 507–517
Publisher
Springer Nature
Publication Date
6 2018
DOI
10.1007/s10552-018-1035-y
ISSN
0957-5243