Conference
Abstract 5157: Prolactin plays a role in regulating fatty acid synthesis and metabolism in the prostate cancer cell line PC-3
Abstract
Abstract
Introduction: Prostate cancer (PCa) metabolism is unique from other cancers due to a high reliance on fatty acid (FA) break down for energy. This phenomenon of FA dependence is exemplified clinically by poor tumor detection by PET scanning, which makes proteins involved in FA synthesis and metabolism interesting therapeutic targets in PCa. Two important proteins for fat metabolism are fatty acid synthase (FASN) and …
Authors
Zantinge SL; Linher-Melville K; Sanli T; Singh G
Volume
72
Pagination
pp. 5157-5157
Publisher
American Association for Cancer Research (AACR)
Publication Date
April 15, 2012
DOI
10.1158/1538-7445.am2012-5157
Conference proceedings
Cancer Research
Issue
8_Supplement
ISSN
0008-5472