Plasma acetaldehyde concentration IS increased following forearm ischemia - Reperfusion exercise

Exercise and ischemia-reperfusion result in oxidative stress in skeletal muscle. Plasma malondialdehyde has traditionally been used as an indicator of this stress, however, other aldehydes are also affected. We have used a recently described, rapid, solid-phase extraction/derivitization HPLC method (Breckenridge, S, et al., J. Chromatography, 694:289-296, 1997) to determine plasma aldehydes in 17 male and female volunteers. Venous plasma …