Journal article
Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder
Abstract
OBJECTIVE: Evidence has suggested that immune imbalance is involved with bipolar disorder (BD); however, its precise mechanism is poorly understood. This study investigated whether biochemical changes in the serum from BD patients could modulate the phenotype of cultured macrophages.
METHODS: Eighteen subjects with BD and five healthy individuals were included in this study. The human monocyte cell line U-937 was activated with phorbol …
Authors
Ferrari P; Parisi MM; Colombo R; Becker M; Fries G; Ascoli BM; Géa LP; Kauer-Sant’anna M; Kapczinski F; Klamt F
Journal
Clinical Psychopharmacology and Neuroscience, Vol. 16, No. 1, pp. 103–108
Publisher
Korean College of Neuropsychopharmacology
Publication Date
February 28, 2018
DOI
10.9758/cpn.2018.16.1.103
ISSN
1738-1088