Therapeutic targeting of ependymoma as informed by...

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

Abstract

Super enhancers regulate oncogenes and other molecular targets in ependymomas, and identification of these genes provides potential therapeutic targets.

Authors

Mack SC; Pajtler KW; Chavez L; Okonechnikov K; Bertrand KC; Wang X; Erkek S; Federation A; Song A; Lee C

Journal

Nature, Vol. 553, No. 7686, pp. 101–105

Publisher

Springer Nature

Publication Date

January 4, 2018

DOI

10.1038/nature25169

ISSN

0028-0836

Associated Experts

John Lee

Associate Professor, Faculty of Health Sciences

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Sheila Singh

Professor, Faculty of Health Sciences