Journal article
Global analysis of prokaryotic tRNA-derived cyclodipeptide biosynthesis
Abstract
BackgroundAmong naturally occurring small molecules, tRNA-derived cyclodipeptides are a class that have attracted attention for their diverse and desirable biological activities. However, no tools are available to link cyclodipeptide synthases identified within prokaryotic genome sequences to their chemical products. Consequently, it is unclear how many genetically encoded cyclodipeptides represent novel products, and which producing organisms …
Authors
Skinnider MA; Johnston CW; Merwin NJ; Dejong CA; Magarvey NA
Journal
BMC Genomics, Vol. 19, No. 1,
Publisher
Springer Nature
Publication Date
December 2018
DOI
10.1186/s12864-018-4435-1
ISSN
1471-2164