Journal article
IL-25 Receptor Expression on Airway Dendritic Cells after Allergen Challenge in Subjects with Asthma
Abstract
RATIONALE: IL-25 is an epithelial-derived cytokine, whose effects are mediated by the IL-25 receptor (IL-17RB), and that has been implicated in the pathogenesis of allergic disease and airway viral responses. Airway myeloid dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs) are professional antigen-presenting cells. pDCs may play a protective role in asthma and are key players in the innate immune response through recognition of …
Authors
Tworek D; Smith SG; Salter BM; Baatjes AJ; Scime T; Watson R; Obminski C; Gauvreau GM; O’Byrne PM
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 193, No. 9, pp. 957–964
Publisher
American Thoracic Society
Publication Date
May 1, 2016
DOI
10.1164/rccm.201509-1751oc
ISSN
1073-449X