Journal article
N-of-1 Randomized Trials of Ultra-Micronized Palmitoylethanolamide in Older Patients with Chronic Pain
Abstract
BackgroundUltra-micronized palmitoylethanolamide (um-PEA) represents an attractive option for chronic pain control in complex older patients at higher risk of adverse effects with traditional analgesics.ObjectiveThe aim of this study was to determine the effectiveness of um-PEA versus placebo on chronic pain intensity and function in individual geriatric patients.DesignWe performed randomized, blinded N-of-1 trials with two 3-week um-PEA versus …
Authors
Germini F; Coerezza A; Andreinetti L; Nobili A; Rossi PD; Mari D; Guyatt G; Marcucci M
Journal
Drugs & Aging, Vol. 34, No. 12, pp. 941–952
Publisher
Springer Nature
Publication Date
December 2017
DOI
10.1007/s40266-017-0506-2
ISSN
1170-229X