Journal article
Thrombin generation in vitro in the presence of by‐passing agents in siblings with severe haemophilia A
Abstract
Previous data have shown an inter-individual difference in the thrombin generating capacity in vitro as well as phenotypic bleeding pattern among patients with severe haemophilia A (FVIII:C activity below 1%). The reason for this is not known. In addition, there are no reports on how thrombin generation may correlate between siblings. In this study, we evaluated and compared thrombin generation in vitro using plasma samples in the presence of …
Authors
KLINTMAN J; BERNTORP E; ASTERMARK J; GROUP OBOTMS
Journal
Haemophilia, Vol. 16, No. 1, pp. e210–e215
Publisher
Wiley
Publication Date
January 2010
DOI
10.1111/j.1365-2516.2009.02132.x
ISSN
1351-8216