Journal article
Risk of Recurrent Venous Thromboembolism in Patients With Common Thrombophilia: A Systematic Review
Abstract
The 2 most common genetic polymorphisms that predispose to a first episode of venous thromboembolism (VTE) are factor V Leiden (FVL) and prothrombin G20210A. However, the effect of these polymorphisms on the risk of recurrent VTE is unclear. We performed a meta-analysis to obtain best estimates of the relative risk of recurrent VTE associated with these genetic polymorphisms. Electronic and manual searches were used to identify cohort studies …
Authors
Ho WK; Hankey GJ; Quinlan DJ; Eikelboom JW
Journal
JAMA Internal Medicine, Vol. 166, No. 7, pp. 729–736
Publisher
American Medical Association (AMA)
Publication Date
April 10, 2006
DOI
10.1001/archinte.166.7.729
ISSN
2168-6106