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Brain Aging and Its Modifiers
Journal article

Brain Aging and Its Modifiers

Abstract

Aging is marked by individual differences and differential vulnerability of cognitive operations and their neural substrates. Cross-sectional studies of brain volume reveal greater age-related shrinkage of the prefrontal cortex (PFC) and the hippocampus than in the entorhinal and primary visual cortex. Longitudinal studies of regional brain shrinkage indicate that when individual differences are controlled, larger and broader shrinkage …

Authors

RAZ N; RODRIGUE KM; HAACKE EM

Journal

Annals of the New York Academy of Sciences, Vol. 1097, No. 1, pp. 84–93

Publisher

Wiley

Publication Date

February 2007

DOI

10.1196/annals.1379.018

ISSN

0077-8923