Effects of TNBS-induced stricture on colonic motor patterns

Objective: To explore the effects of TNBS-induced stricture on colonic motor patterns. Methods: Thirty-two SD rats were divided randomly and equally into four groups: A, B, C, and D according to the treatment TNBS, TNBS+Smecta, Smecta, and normal saline (normal control), respectively. All rats were killed 8 days later and using spatiotemporal mapping to investigate the motor activities of the proximal colon. Results: Formation of strictures …