Journal article
Statin Use and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Treated with Abiraterone Acetate
Abstract
BACKGROUND: Although statin use has been associated with favorable effects in various solid malignancies, no conclusive evidence is available at present. Statins are safe and inexpensive, and may synergize with novel antiandrogen agents abiraterone via pharmacokinetic interactions and decrease substrate availability for de novo androgen biosynthesis.
OBJECTIVE: To determine whether statin use affects survival in patients with metastatic …
Authors
Di Lorenzo G; Sonpavde G; Pond G; Lucarelli G; Rossetti S; Facchini G; Scagliarini S; Cartenì G; Federico P; Daniele B
Journal
European Urology Focus, Vol. 4, No. 6, pp. 874–879
Publisher
Elsevier
Publication Date
December 2018
DOI
10.1016/j.euf.2017.03.015
ISSN
2405-4569