Journal article
Integrated Time-Resolved Fluorescence and Diffuse Reflectance Spectroscopy Instrument for Intraoperative Detection of Brain Tumor Margin
Abstract
Time-resolved fluorescence (TRF) and diffuse reflectance (DR) spectroscopy are two optical biopsy modalities that have been studied in tumor diagnosis. Combination of TRF and DR spectroscopy allows us to obtain more features such as fluorescence intensity, lifetime, and optical properties; thus, potentially improving the tissue diagnostic accuracy. In this paper, an integrated TRF-DR spectroscopy instrument was developed to acquire TRF spectra …
Authors
Nie Z; Du Le VN; Cappon D; Provias J; Murty N; Hayward JE; Farrell TJ; Patterson MS; McMillan W; Fang Q
Journal
IEEE Journal of Selected Topics in Quantum Electronics, Vol. 22, No. 3, pp. 49–57
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
DOI
10.1109/jstqe.2015.2510964
ISSN
1077-260X