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Analytical validation of a standardized scoring...
Conference

Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration

Abstract

Pathological analysis of the nuclear proliferation biomarker Ki67 has multiple potential roles in breast and other cancers. However, clinical utility of the immunohistochemical (IHC) assay for Ki67 immunohistochemistry has been hampered by unacceptable between-laboratory analytical variability. The International Ki67 Working Group has conducted a series of studies aiming to decrease this variability and improve the evaluation of Ki67. This …

Authors

Leung SCY; Nielsen TO; Zabaglo L; Arun I; Badve SS; Bane AL; Bartlett JMS; Borgquist S; Chang MC; Dodson A

Volume

2

Publisher

Springer Nature

DOI

10.1038/npjbcancer.2016.14

Conference proceedings

npj Breast Cancer

Issue

1

ISSN

2374-4677