Meta-analysis of 74,046 individuals identifies 11...

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Abstract

Philippe Amouyel, Julie Williams, Gerard Schellenberg, Sudha Seshadri and colleagues report a meta-analysis of genome-wide association studies for late-onset Alzheimer's disease in 17,008 cases and 37,154 controls with replication in an additional 8,572 cases and 11,312 controls. They identify 11 loci newly associated with Alzheimer's disease.

Authors

Lambert J-C; Ibrahim-Verbaas CA; Harold D; Naj AC; Sims R; Bellenguez C; Jun G; DeStefano AL; Bis JC; Beecham GW

Journal

Nature Genetics, Vol. 45, No. 12, pp. 1452–1458

Publisher

Springer Nature

Publication Date

December 1, 2013

DOI

10.1038/ng.2802

ISSN

1061-4036

Associated Experts

James Raymond Gilbert

Professor Emeritus, Faculty of Health Sciences

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