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The Anatomy and Physiology of the Sinoatrial...
Journal article

The Anatomy and Physiology of the Sinoatrial Node—A Contemporary Review

Abstract

The sinoatrial node is the primary pacemaker of the heart. Nodal dysfunction with aging, heart failure, atrial fibrillation, and even endurance athletic training can lead to a wide variety of pathological clinical syndromes. Recent work utilizing molecular markers to map the extent of the node, along with the delineation of a novel paranodal area intermediate in characteristics between the node and the surrounding atrial muscle, has shown that …

Authors

MONFREDI O; DOBRZYNSKI H; MONDAL T; BOYETT MR; MORRIS GM

Journal

Pacing and Clinical Electrophysiology, Vol. 33, No. 11, pp. 1392–1406

Publisher

Wiley

Publication Date

11 2010

DOI

10.1111/j.1540-8159.2010.02838.x

ISSN

0147-8389