subject area of
- Failure of human rhombic lip differentiation underlies medulloblastoma formation Academic Article
- Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis Academic Article
- LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML Academic Article
- Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C Academic Article
- Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C Academic Article
- RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity Academic Article
- Structure-activity studies on N -Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation Academic Article
- The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance Academic Article