Factor XIa
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A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction Journal Articles
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A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss Journal Articles
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Analysis of Inhibition Rate Enhancement by Covalent Linkage of Antithrombin to Heparin as a Potential Predictor of Reaction Mechanism Journal Articles
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Are Ticks the Answer to Medical Device-Associated Clotting? Journal Articles
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Effect of the Factor XIa Inhibitor Asundexian According to Baseline Infarct Pattern and on MRI Covert Infarct Outcomes Journal Articles
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Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial Journal Articles
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Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway Journal Articles
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Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation Journal Articles
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Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Journal Articles
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MAA868 locks factor XIa in a zymogen-like state Journal Articles
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Milvexian for the Prevention of Venous Thromboembolism Journal Articles
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Milvexian vs apixaban for stroke prevention in atrial fibrillation: The LIBREXIA atrial fibrillation trial rationale and design. Journal Articles
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Rationale and design of the AXIOMATIC-SSP phase II trial: Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events for Secondary Stroke Prevention Journal Articles
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Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins Journal Articles
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Safety and efficacy of factor XIa inhibition with milvexian for secondary stroke prevention (AXIOMATIC-SSP): a phase 2, international, randomised, double-blind, placebo-controlled, dose-finding trial Journal Articles
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Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa Journal Articles
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Selection and in vitro and in vivo characterization of a Kunitz protease inhibitor domain of protease nexin 2 variant that inhibits factor XIa without inhibiting plasmin Journal Articles
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Transfusion-Induced Specific Anti–Factor XI Inhibitor in a Patient with Previously Unrecognized Factor XI Deficiency Journal Articles