Journal article
Clonidine Does Not Reduce Pain or Opioid Consumption After Noncardiac Surgery
Abstract
BACKGROUND: Clonidine is an α2-adrenoceptor agonist, which has analgesic properties. However, the analgesic efficacy of perioperative clonidine remains unclear. We, therefore, tested the hypothesis that clonidine reduces both pain scores and cumulative opioid consumption during the initial 72 hours after noncardiac surgery.
METHODS: Six hundred twenty-four patients undergoing elective noncardiac surgery under general and spinal anesthesia were …
Authors
Turan A; Babazade R; Kurz A; Devereaux PJ; Zimmerman NM; Hutcherson MT; Naylor AJ; Ali Sakr Esa W; Parlow J; Gilron I
Journal
Anesthesia & Analgesia, Vol. 123, No. 3, pp. 749–757
Publisher
Wolters Kluwer
Publication Date
September 2016
DOI
10.1213/ane.0000000000001356
ISSN
0003-2999