Journal article
Bisphosphonates for treatment of osteoporosis: expected benefits, potential harms, and drug holidays.
Abstract
OBJECTIVE: To outline the efficacy and risks of bisphosphonate therapy for the management of osteoporosis and describe which patients might be eligible for bisphosphonate "drug holiday."
QUALITY OF EVIDENCE: MEDLINE (PubMed, through December 31, 2012) was used to identify relevant publications for inclusion. Most of the evidence cited is level II evidence (non-randomized, cohort, and other comparisons trials).
Authors
Brown JP; Morin S; Leslie W; Papaioannou A; Cheung AM; Davison KS; Goltzman D; Hanley DA; Hodsman A; Josse R
Journal
Canadian Family Physician, Vol. 60, No. 4, pp. 324–333
Publication Date
4 2014
ISSN
0008-350X