Journal article
Cloning and characterization of alternatively spliced isoforms of Dp71
Abstract
Dp71, a C-terminal isoform of dystrophin, has been identified as the major DMD gene product in many nonmuscle tissues. In this report, reverse transcriptase-polymerase chain reaction (RT-PCR) was used to clone and characterize four alternatively spliced Dp71 transcripts from cultured human amniocytes. The cDNAs encoding these Dp71 transcripts were shown to be alternatively spliced for exons 71 and/or 78. RT-PCR analysis also revealed that Dp71 …
Authors
C. AR; Howard PL; D'Souza VN; Klamut HJ; Ray PN
Journal
Human Molecular Genetics, Vol. 4, No. 9, pp. 1475–1483
Publisher
Oxford University Press (OUP)
Publication Date
1995
DOI
10.1093/hmg/4.9.1475
ISSN
0964-6906