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Cloning and characterization of alternatively...
Journal article

Cloning and characterization of alternatively spliced isoforms of Dp71

Abstract

Dp71, a C-terminal isoform of dystrophin, has been identified as the major DMD gene product in many nonmuscle tissues. In this report, reverse transcriptase-polymerase chain reaction (RT-PCR) was used to clone and characterize four alternatively spliced Dp71 transcripts from cultured human amniocytes. The cDNAs encoding these Dp71 transcripts were shown to be alternatively spliced for exons 71 and/or 78. RT-PCR analysis also revealed that Dp71 …

Authors

C. AR; Howard PL; D'Souza VN; Klamut HJ; Ray PN

Journal

Human Molecular Genetics, Vol. 4, No. 9, pp. 1475–1483

Publisher

Oxford University Press (OUP)

Publication Date

1995

DOI

10.1093/hmg/4.9.1475

ISSN

0964-6906