selected scholarly activity
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chapters
- Cell Surface GRP78. 63-85. 2018
- Chapter 4 Cell Surface GRP78 A Novel Regulator of Tissue Factor Procoagulant Activity. 63-85. 2018
- Endoplasmic Reticulum Stress and the Unfolded Protein Response in Lipid Metabolism and Obesity. 231-256. 2012
- Homocysteine as an Endogenous Toxin in Cardiovascular Disease. 349-378. 2009
- Role of Hyperhomocysteinemia in Atherosclerosis. 358-379. 2006
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conferences
- Investigating a novel recombinant antibody to attenuate prostate cancer progression by targeting cell surface GRP78.. Journal of Clinical Oncology. 206-206. 2019
- Prostate cancer-derived anti-GRP78 autoantibodies compromise the blood-brain barrier and accelerate atherosclerosis progression in vivo.. Journal of Clinical Oncology. 205-205. 2019
- Hepatic Cholesterol Dysregulation in SR-B1/ApoE dKO Mice. Atherosclerosis Plus. 38-39. 2018
- Loss-of-function PCSK9 Mutants Evade the Unfolded Protein Response Sensor, GRP78, and Fail to Induce Endoplasmic Reticulum Stress when Retained. Atherosclerosis Plus. 139-139. 2018
- TDAG51 is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells. Atherosclerosis Plus. 100-100. 2018
- Targeting Liver ATP-Citrate Lyase with Bempedoic Acid: A Complementary LDL-C Lowering Strategy for Treating Hypercholesterolemia. Atherosclerosis Plus. 17-17. 2018
- Cell surface GRP78 activation by anti-GRP78 autoantibodies confers prostate tumour growth via tissue factor activation. Thrombosis Research. S226-S226. 2018
- Restoration of hepatic TDAG51 expression improves insulin signaling and reduces weight gain in mouse models of non‐alcoholic fatty liver disease. The FASEB Journal. 2018
- Cell surface GRP78 activation by anti-GRP78 autoantibodies in relation to prostate tumour growth via tissue factor activation.. Journal of Clinical Oncology. 31-31. 2018
- LB-S&T-32 CHARACTERIZING THE ROLE OF ANTI-GRP78 AUTOANTIBODIES IN PROSTATE CANCER PROGRESSION. Investigative Urology. E350-E350. 2016
- Effect of anti-GRP78 autoantibodies on prostate cancer progression through tissue factor procoagulant activity.. Journal of Clinical Oncology. 258-258. 2016
- Il-6 Mediated Hyperpolarization Of Profibrotic Macrophages Is Dependent On Spliced Xbp1. American Journal of Respiratory and Critical Care Medicine. 2016
- Contribution of Anti-GRP78 autoantibodies to prostate cancer progression through tissue factor procoagulant activity. BJU International. 85-86. 2015
- Activation of cell surface grp78 by anti-grp78 autoantibodies augments endothelial cell activation and accelerates atherosclerotic lesion development. Atherosclerosis. e119-e119. 2014
- AMP-activated Protein Kinase is Critical for Regulating Cholesterol Homeostasis in Macrophages. Circulation. 2013
- 315 ERP46 MEDIATES PROSTATE CANCER TUMORIGENESIS IN VITRO BY INHIBITING ADIPONECTIN-INDUCED TUMOR-SUPPRESSIVE EFFECTS- LINKING OBESITY TO PROSTATE CANCER. Investigative Urology. E128-E128. 2013
- ER stress and a chronic inflammatory response are induced in an Angiotensin II/DOCA salt model of chronic kidney disease.. The FASEB Journal. 2013
- 156 LKB1 DRIVES ADIPONECTIN RECEPTOR 1 (ADIPOR1) EXPRESSION IN CLEAR CELL RENAL CELL CARCINOMA (CCRCC): FROM TUMOR DEVELOPMENT TO DISEASE CHARACTERISTICS. Investigative Urology. E64-E64. 2012
- Binding of anti-GRP78 autoantibodies to cell surface GRP78 promotes cancer progression by activating tissue factor procoagulant activity. Thrombosis Research. S158-S158. 2012
- Determining how 4‐phenylbutyrate inhibits tunicamycininduced acute kidney injury. The FASEB Journal. 2012
- Hypertension induces proteinuria and renal fibrosis associated with endoplasmic reticulum (ER) stress in the Dahl salt sensitive rat. The FASEB Journal. 2012
- TDAG51 overexpression mediates proximal tubule epithelial cell apoptosis through its accumulation in the nucleus. The FASEB Journal. 2012
- 233 ACTIVATION OF ADIPONECTIN RECEPTOR 1 (ADIPOR1) WHICH IS UNDER-EXPRESSED IN KIDNEY CANCER INDUCES TUMOR SUPRESSION. Investigative Urology. E95-E95. 2011
- 396 PRESENCE OF GRP78 ON THE CELL SURFACE OF KIDNEY CANCER CELLS CORRELATES WITH INCREASED ANTI-GRP78 AUTOANTIBODY TITRES IN KIDNEY CANCER PATIENTS- A POTENTIAL NOVEL DIAGNOSTIC MARKER. Investigative Urology. E160-E160. 2011
- ER stress inducing agents that cause induction of TDAG51 and epithelial adhesion disruption result in epithelial to mesenchymal transition via β‐catenin signaling. The FASEB Journal. 2011
- Loss of TDAG51 attenuates aorta smooth muscle to osteoblast trans-differentiation and calcification. The FASEB Journal. 2011
- The gene TDAG51 facilitates the phosphorylation of eIF2α in mouse embryonic fibroblasts. The FASEB Journal. 2011
- The small molecule chemical chaperone 4‐Phenylbutyrate inhibits epithelial‐to‐mesenchymal transition in human renal proximal tubular epithelial cells. The FASEB Journal. 2011
- The Chemical Chaperone 4-Phenylbutyrate Attenuates Adipogenesis by Modulating the Unfolded Protein Response. Obesity. S70-S70. 2009
- Intracellular localization of TDAG51 modulates its effect on cell death. The FASEB Journal. 2009
- No longer just an intermediate: Cystathionine protects against endoplasmic reticulum stress induced lipid accumulation and apoptotic cell death. Journal of Inherited Metabolic Disease. 8-8. 2008
- Macrophage Differentiation Involves Activation of the Unfolded Protein Response. The FASEB Journal. 2008
- Rosiglitazone protects against beta cell destruction in ZDF (Type 2) diabetic rats. The FASEB Journal. 2008
- Targeting and inactivation of endoplasmic reticulum chaperones by L‐homocysteine: a pathway to ER stress. The FASEB Journal. 2008
- Contributions of Endoplasmic Reticulum (ER) Stress to Cardiovascular Disease. CURRENT ADVANCES IN HEART DISEASE. 57-58. 2008
- Deficiency in TDAG51 Decreases Atherosclerotic Lesion Development in ApoE-Deficient Mice.. Blood. 3940-3940. 2006
- TDAG51 Deficiency Promotes Migration and Proliferation of Mouse Embryonic Fibroblasts.. Blood. 3941-3941. 2006
- Hyaluronan and inflammation - Causes and consequences. Journal of Histochemistry and Cytochemistry. S10-S10. 2004
- Endoplasmic reticulum stress in mucosal smooth muscle cells upregulates hyaluronan deposition and leukocyte adhesion. Gastroenterology. A497-A497. 2003
- Homocysteine enhances cholesterol biosynthesis in cultured human smooth muscle cells and hepatocytes.. Blood. 449A-449A. 1999
- Preparation and characterization of a humanized 520C9 single-chain Fv human interleukin-2 fusion protein.. Cancer Biotherapy and Radiopharmaceuticals. 52-52. 1998
- Differential expression and synthesis of GRP78 and HSP70 by homocysteine.. Blood. 1265-1265. 1997
- Homocysteine alters mitochondrial gene expression, function and structure.. Blood. 1358-1358. 1997
- Mutations in the glycosaminoglycan-binding domain of heparin cofactor II result in variants with increased thrombin inhibitory activity.. Blood. 120-120. 1997
- Localization of the thrombin-binding domain on prothrombin fragment 2. Thrombosis and Haemostasis. P1736-P1736. 1997
- Prothrombin fragment 2 modulates thrombin function. Thrombosis and Haemostasis. P1752-P1752. 1997
- AN EVALUATION OF FORMAL EXPERIMENTAL-DESIGN PROCEDURES FOR HYDROCYCLONE MODELING. HYDROCYCLONES. 31-49. 1992
- INVOLVEMENT OF THE NH2-TERMINAL DOMAIN OF ANTITHROMBIN-III IN HEPARIN BINDING AND COMPLEX-FORMATION WITH ALPHA-THROMBIN. Thrombosis and Haemostasis. 670-670. 1991
- SITE-DIRECTED MUTAGENESIS OF ALANINE 382 OF HUMAN ANTITHROMBIN-III (AT-III). Thrombosis and Haemostasis. 669-669. 1991
- Molecular Defects in Human Antithrombin III Deficiency. RECOMBINANT TECHNOLOGY IN HEMOSTASIS AND THROMBOSIS. 133-146. 1991
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journal articles
- GDF10 is a negative regulator of vascular calcification.. Journal of Biological Chemistry. 300:107805. 2024
- Corrigendum to "PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease" [Metabolism Volume 150, January 2024, 155736, PMID: 7967646].. Metabolism: Clinical and Experimental. 161:156032. 2024
- Small Molecules Targeting GRP78 Mitigate Anti- GRP78 Autoantibody-Mediated Tissue Factor Procoagulant Activity in Cultured Endothelial Cells. Journal of Thrombosis and Haemostasis. 22:3290-3304. 2024
- Fatal attractions that trigger inflammation and drive atherosclerotic disease. European Journal of Clinical Investigation. 54:e14169. 2024
- Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice. Journal of Biological Chemistry. 300:105655-105655. 2024
- Reduced plasma GDF10 levels are positively associated with cholesterol impairment and childhood obesity. Scientific Reports. 14:1805. 2024
- PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease. Metabolism: Clinical and Experimental. 150:155736-155736. 2024
- Repurposing Two Old Friends to Fight Cancer: Caffeine and Statins. Cancer Research. 83:2091-2092. 2023
- A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice. Nutrients. 15:2410-2410. 2023
- Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1): A Multifaceted Cell Survival Factor that Drives Metabolic Disease. Engineering. 20:9-18. 2023
- Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity. Kidney360. 3:1394-1410. 2022
- Stressing the endoplasmic reticulum response as a diagnostic tool for sepsis. ANNALS OF TRANSLATIONAL MEDICINE. 10:812-812. 2022
- Scratching the Surface—An Overview of the Roles of Cell Surface GRP78 in Cancer. Biomedicines. 10:1098-1098. 2022
- The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases. Metabolites. 12:215-215. 2022
- Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance. Nature Communications. 13:770. 2022
- Endoplasmic reticulum stress derives neurodegeneration in the spinal cord of Sandhoff disease mice. Molecular Genetics and Metabolism. 135:S127-S127. 2022
- Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium. Frontiers in Physiology. 13:1023397. 2022
- Salsalate reduces atherosclerosis through AMPKβ1 in mice. Molecular Metabolism. 53:101321-101321. 2021
- TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease. Cell Death and Disease. 12:921. 2021
- Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin. Journal of Biological Chemistry. 297:101177-101177. 2021
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Glucose‐regulated protein (
GRP78 ) is an important cell surface receptor for viral invasion, cancers, and neurological disorders. IUBMB Life. 73:843-854. 2021 - The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury. Journal of Clinical Investigation. 131:128650. 2021
- Calcium as a reliable marker for the quantitative assessment of endoplasmic reticulum stress in live cells. Journal of Biological Chemistry. 296:100779-100779. 2021
- Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue. European Respiratory Journal. 56:2001123-2001123. 2020
- TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells. Arteriosclerosis, Thrombosis and Vascular Biology. 40:1664-1679. 2020
- Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles. Cell Reports. 31:107597-107597. 2020
- Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice. JHEP Reports. 1:418-429. 2019
- GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury. Molecular Metabolism. 27:62-74. 2019
- 4‐Phenylbutyrate protects against atherosclerotic lesion growth by increasing the expression of HSP25 in macrophages and in the circulation of Apoe −/− mice. The FASEB Journal. 33:8406-8422. 2019
- Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice. Journal of Biological Chemistry. 294:9037-9047. 2019
- Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy. Journal of Biological Chemistry. 294:7755-7768. 2019
- MP81-18 INVESTIGATING A NOVEL RECOMBINANT ANTIBODY TO ATTENUATE PROSTATE CANCER PROGRESSION BY TARGETING CELL SURFACE GRP78. Investigative Urology. 201. 2019
- Investigating a novel recombinant antibody to attenuate prostate cancer progression by targeting cell surface GRP78. European Urology Open Science. 18:e1336-e1336. 2019
- Prostate cancer-derived anti-GRP78 autoantibodies compromise the blood-brain barrier and accelerate atherosclerosis progression in vivo. European Urology Open Science. 18:e1155-e1155. 2019
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IL ‐6 mediatesER expansion during hyperpolarization of alternatively activated macrophages. Immunology and Cell Biology. 97:203-217. 2019 - GRP78 (Glucose-Regulated Protein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4). Hypertension. 73:390-398. 2019
- The trypan blue cellular debris assay: a novel low-cost method for the rapid quantification of cell death. MethodsX. 6:1174-1180. 2019
- Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions. JCI insight. 3:99363. 2018
- Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice. Journal of Biological Chemistry. 293:14689-14706. 2018
- Thrombotic characteristics of extracellular vesicles derived from prostate cancer cells. Prostate. 78:953-961. 2018
- MAPping the kinase landscape of macrophage activation. Journal of Biological Chemistry. 293:9910-9911. 2018
- Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death. Toxicology and Applied Pharmacology. 349:1-7. 2018
- Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation. Circulation Research. 122:1545-1554. 2018
- Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. Journal of Biological Chemistry. 293:7329-7343. 2018
- Cell surface GRP78 activation by anti‐GRP78 autoantibodies in relation to prostate tumour growth via tissue factor activation.. The FASEB Journal. 32:804.13-804.13. 2018
- Loss‐of‐function PCSK9 mutants evade the unfolded protein response sensor, GRP78, and fail to induce endoplasmic reticulum stress when retained. The FASEB Journal. 32:793.7-793.7. 2018
- PCSK9 REDUCES HEPATIC LIPID CONTENT AND CONFERS PROTECTION AGAINST ER STRESS AND ROS IN HEPG2 CELLS. The FASEB Journal. 32:539.8-539.8. 2018
- TDAG51 is a key modulator of vascular calcification and osteogenic transdifferentiation of arterial smooth muscle cells. The FASEB Journal. 32:533.90-533.90. 2018
- Disrupting the interaction between anti-GRP78 autoantibodies and cell surface GRP78 with low molecular weight heparin as a treatment for prostate cancer. European Urology Open Science. 17:e509-e509. 2018
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Separate roles of
IL ‐6 and oncostatin M in mouse macrophage polarization in vitro and in vivo. Immunology and Cell Biology. 96:257-272. 2018 - Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering. Arteriosclerosis, Thrombosis and Vascular Biology. 38:26-39. 2018
- The Pleckstrin homology like domain family member, TDAG51, is temporally regulated during skeletal muscle regeneration. Biochemical and Biophysical Research Communications. 495:499-505. 2018
- Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor. Journal of Biological Chemistry. 292:21180-21192. 2017
- Endoplasmic reticulum protein ERp46 in prostate adenocarcinoma. Oncology Letters. 13:3624-3630. 2017
- Cell surface GRP78 activation by anti-GRP78 autoantibodies confers prostate tumour growth via tissue factor activation. European Urology Open Science. 16:e157-e158. 2017
- Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism. Journal of Biological Chemistry. 292:1510-1523. 2017
- Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism. Journal of Biological Chemistry. 292:1510-1523. 2017
- Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis. Nature Communications. 7:13457. 2016
- Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth. Journal of the American Heart Association. 5:e003945. 2016
- GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis. Journal of Pathology. 239:411-425. 2016
- Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.. Journal of Biological Chemistry. 290:28725-28725. 2015
- Abstract 533: Salicylate Restores Macrophage Cholesterol Homeostasis via Activation of AMP-Activated Protein Kinase. Arteriosclerosis, Thrombosis and Vascular Biology. 35. 2015
- Salicylate improves macrophage cholesterol homeostasis via activation of Ampk. Journal of Lipid Research. 56:1025-1033. 2015
- 4-PBA-treated drinking water protects against atherosclerotic lesion growth in apoE-/- mice.. Atherosclerosis. 235:e126-e126. 2014
- Macrophage proliferation in mouse models of atherosclerosis. Atherosclerosis. 235:e125-e126. 2014
- Abstract 655: 4-Phenylbutyrate in Drinking Water Reduced Atherosclerotic Lesion Growth in ApoE-/- Mice by Modifying Monocyte-Macrophage Differentiation. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression. Clinical and Experimental Metastasis. 31:169-183. 2014
- Endoplasmic Reticulum Protein ERp46 in Renal Cell Carcinoma. PLoS ONE. 9:e90389-e90389. 2014
- Abstract 18333: Tdag51 Deficiency Protects Against Aortic Vascular Calcification by Attenuating Smooth Muscle Cell Death and Osteoblastic Trans-Differentiation. Circulation. 128. 2013
- Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis. Circulation. 127:2523-2534. 2013
- Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression. Journal of the American Heart Association. 2:e000134. 2013
- 939 ERp46 mediates prostate cancer tumorigenesis in vitro by inhibiting adiponectin-induced tumor-suppressive effects – linking obesity to prostate cancer. European Urology Open Science. 12:e939-e939. 2013
- Prenatal stress enhances severity of atherosclerosis in the adult apolipoprotein E-deficient mouse offspring via inflammatory pathways. Journal of Developmental Origins of Health and Disease. 4:90-97. 2013
- Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo. British Journal of Cancer. 108:327-333. 2013
- Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis. Diabetes. 62:158-169. 2013
- Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate Cancer. PLoS ONE. 8:e70047-e70047. 2013
- Cystathionine Protects against Endoplasmic Reticulum Stress-induced Lipid Accumulation, Tissue Injury, and Apoptotic Cell Death. Journal of Biological Chemistry. 287:31994-32005. 2012
- TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium. American Journal of Physiology - Renal Physiology. 303:F467-F481. 2012
- ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death. American Journal of Physiology - Renal Physiology. 303:F266-F278. 2012
- Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase. Journal of Biological Chemistry. 287:7603-7614. 2012
- Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential. Biochemistry Research International. 2012:1-13. 2012
- ER Stress‐Induced SREBP‐2 Activation Contributes to Lipid Accumulation in Tubular Nephrotoxicity. The FASEB Journal. 25:1002.8-1002.8. 2011
- Interrelationship Between Cardiac Hypertrophy, Heart Failure, and Chronic Kidney Disease. Circulation Research. 108:629-642. 2011
- Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes. Journal of Thrombosis and Haemostasis. 9:582-592. 2011
- Endoplasmic reticulum stress and lipid dysregulation. Expert Reviews in Molecular Medicine. 13:e4. 2011
- Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions. The FASEB Journal. 25:576-589. 2011
- Hydrogen sulfide in the pathogenesis of atherosclerosis and its therapeutic potential. Expert Review of Clinical Pharmacology. 4:97-108. 2011
- Immunohistochemical Detection of the Unfolded Protein Response in Atherosclerotic Plaques. Methods in Enzymology. 489:23-46. 2011
- α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells. Nature Communications. 2:307. 2011
- Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores. Journal of Biological Chemistry. 285:28912-28923. 2010
- Development of a continuous assay for the measurement of tissue factor procoagulant activity on intact cells. Laboratory Investigation. 90:953-962. 2010
- The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response. Journal of Lipid Research. 50:2486-2501. 2009
- The Unfolded Protein Response in Health and Disease. Antioxidants and Redox Signaling. 11:2279-2287. 2009
- The methylenetetrahydrofolate reductase C677T mutation induces cell‐specific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site‐specific cancer risk modification. International Journal of Cancer. 124:1999-2005. 2009
- Natural Orifice Translumenal Endoscopic Surgery (NOTES). Annals of the Royal College of Surgeons of England. 91:192-194. 2009
- Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms. BioFactors. 35:120-129. 2009
- Mouse models of cystathionine β‐synthase deficiency reveal significant threshold effects of hyperhomocysteinemia. The FASEB Journal. 23:883-893. 2009
- ER Stress and Lipogenesis: A Slippery Slope toward Hepatic Steatosis. Developmental Cell. 15:795-796. 2008
- Immunohistochemical detection of N-homocysteinylated proteins in humans and mice. Biomedicine and Pharmacotherapy. 62:473-479. 2008
- Macrophage Function and Its Impact on Atherosclerotic Lesion Composition, Progression, and Stability. Arteriosclerosis, Thrombosis and Vascular Biology. 28:1413-1415. 2008
- Novel Function of PERK as a Mediator of Force-induced Apoptosis. Journal of Biological Chemistry. 283:23462-23472. 2008
- Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice. The FASEB Journal. 22:2569-2578. 2008
- Post-Communist Transitional Justice in Albania. East European Politics and Societies. 22:373-401. 2008
- Role of Endoplasmic Reticulum Calcium Disequilibria in the Mechanism of Homocysteine-Induced ER Stress. Antioxidants and Redox Signaling. 9:1863-1874. 2007
- Increased Endoplasmic Reticulum Stress in Atherosclerotic Plaques Associated With Acute Coronary Syndrome. Circulation. 116:1214-1216. 2007
- The new powers of arrest: Plus a change: More of the same or major change?. Criminal Law Review. 459-471. 2007
- Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2. International Journal of Biochemistry and Cell Biology. 39:1843-1851. 2007
- Homocysteinylation of Metallothionein Impairs Intracellular Redox Homeostasis. Arteriosclerosis, Thrombosis and Vascular Biology. 27:8-11. 2007
- Prothrombotic Effects of Hyperhomocysteinemia and Hypercholesterolemia in ApoE-Deficient Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 27:233-240. 2007
- Proteasomal Regulation of Cardiac Hypertrophy. Circulation. 114:1796-1798. 2006
- Peroxynitrite Causes Endoplasmic Reticulum Stress and Apoptosis in Human Vascular Endothelium. Arteriosclerosis, Thrombosis and Vascular Biology. 25:2623-2629. 2005
- Getting a GRP on Tissue Factor Activation. Arteriosclerosis, Thrombosis and Vascular Biology. 25:1529-1531. 2005
- Activation of the Unfolded Protein Response Occurs at All Stages of Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice. Circulation. 111:1814-1821. 2005
- Glucosamine-Induced Endoplasmic Reticulum Stress Promotes ApoB100 Degradation. Arteriosclerosis, Thrombosis and Vascular Biology. 25:571-577. 2005
- Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. Journal of Cell Science. 118:89-99. 2005
- Activation of mesangial cell MAPK in responseto homocysteine. Kidney International. 66:733-745. 2004
- Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice. Circulation. 110:207-213. 2004
- Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death and Differentiation. 11:S56-S64. 2004
- PEROXYNITRITE INDUCES ER-STRESS THROUGH A MECHANISM INVOLVING ER-CA2+ DEPLETION LEADING TO PROGRAMMED CELL DEATH. Cardiovascular Pathology. 13:108-108. 2004
- POTENTIAL ROLE FOR GLYCOGEN SYNTHASE KINASE (GSK)-3 IN ENDOPLASMIC RETICULUM (ER) STRESS-INDUCED ATHEROSCLEROSIS. Cardiovascular Pathology. 13:29-29. 2004
- Overexpression of the Endoplasmic Reticulum 60 Protein ER-60 Downregulates ApoB100 Secretion by Inducing Its Intracellular Degradation via a Nonproteasomal Pathway: Evidence for an ER-60-Mediated and pCMB-Sensitive Intracellular Degradative Pathway. Biochemistry. 43:4819-4831. 2004
- Oligodendroglioma. Current Treatment Options in Oncology. 4:479-490. 2003
- Endoplasmic Reticulum Stress Induces Hyaluronan Deposition and Leukocyte Adhesion. Journal of Biological Chemistry. 278:47223-47231. 2003
- Hyperhomocysteinemia and its role in the development of atherosclerosis. Clinical Biochemistry. 36:431-441. 2003
- TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia. Journal of Biological Chemistry. 278:30317-30327. 2003
- Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice. Atherosclerosis. 168:255-262. 2003
- Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors. Journal of Biological Chemistry. 278:20915-20924. 2003
- Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity. Journal of Biological Chemistry. 278:17438-17447. 2003
- Choriocarcinoma of the colon. Diseases of the Colon and Rectum. 46:264-266. 2003
- Novel bioabsorbable interbody fusion spacer–assisted fusion for correction of spinal deformity. Neurosurgical Focus. 14:1-6. 2003
- Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton. Journal of Biological Chemistry. 277:47106-47113. 2002
- A Novel Approach to Tumor Suppression with Microencapsulated Recombinant Cells. Human gene therapy. Clinical development. 13:1157-1166. 2002
- Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface. Journal of Biological Chemistry. 277:7529-7539. 2002
- Dietary Supplementation With Methionine and Homocysteine Promotes Early Atherosclerosis but Not Plaque Rupture in ApoE-Deficient Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 21:1470-1476. 2001
- Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. Journal of Clinical Investigation. 107:1263-1273. 2001
- Placental Transforming Growth Factor-β Is a Downstream Mediator of the Growth Arrest and Apoptotic Response of Tumor Cells to DNA Damage and p53 Overexpression. Journal of Biological Chemistry. 275:20127-20135. 2000
- Expression and synthesis of alternatively spliced variants of Dp71 in adult human brain. Neuromuscular Disorders. 10:187-193. 2000
- Radioimmunodetection: technical problems and methods of improvement. European Journal of Surgical Oncology. 25:529-539. 1999
- Comparison of Heparin- and Dermatan Sulfate-mediated Catalysis of Thrombin Inactivation by Heparin Cofactor II. Journal of Biological Chemistry. 274:27597-27604. 1999
- Homocysteine-Induced Endoplasmic Reticulum Stress and Growth Arrest Leads to Specific Changes in Gene Expression in Human Vascular Endothelial Cells. Blood. 94:959-967. 1999
- Preparation and characterization of a recombinant humanized single-chain Fv antibody/human interleukin-2 fusion protein directed against the HER-2/neu (c-erbB2) proto-oncogene product, p185. Tumor Targeting. 4:105-114. 1999
- Dystrophin isoforms Dp71 and Dp427 have distinct roles in myogenic cells. Muscle and Nerve. 22:16-27. 1999
- Homocysteine-dependent Alterations in Mitochondrial Gene Expression, Function and Structure. Journal of Biological Chemistry. 273:30808-30817. 1998
- Characterization of the stress-inducing effects of homocysteine. Biochemical Journal. 332:213-221. 1998
- Localization of the Thrombin-binding Domain on Prothrombin Fragment 2. Journal of Biological Chemistry. 273:8932-8939. 1998
- Dexamethasone-induced suppression of apoptosis in human neutrophils requires continuous stimulation of new protein synthesis. Journal of Leukocyte Biology. 61:224-230. 1997
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