Journal article
Quantification of mitochondrial sublimons in human fibrillating atria
Abstract
Supraventricular tachycardias, including AF (atrial fibrillation), and mtDNA (mitochondrial DNA) deletions may lead to dilated cardiomyopathy. It is unknown whether mtDNA function is impaired in the human atrium in AF. In the present study, we investigated the role of rearranged mtDNA 'sublimons' in the pathogenesis of AF. Right atrial biopsies were collected from 38 patients in AF and 35 patients with SR (sinus rhythm) undergoing elective …
Authors
MAAROUF N; Gavin A; CARTER ND; SYRRIS P; YUSUF S; CAMM JA; POLEINIKI J; Al-SAADY NM
Journal
Clinical Science, Vol. 106, No. 6, pp. 653–659
Publisher
Portland Press
Publication Date
June 1, 2004
DOI
10.1042/cs20030252
ISSN
0143-5221