Journal article
Effect of Interleukin-2 on the Airway Response to Antigen in the Rat
Abstract
To evaluate the hypothesis that lymphocyte stimulation can modify the bronchoconstrictive response to inhalational challenge with an allergen, we administered interleukin-2 (IL-2), an important lymphokine in lymphocyte activation and proliferation, to actively sensitized rats. Brown Norway rats received either human recombinant IL-2 (n = 8) or its vehicle (n = 7) twice a day from the ninth to the fourteenth day after active sensitization to …
Authors
Renzi PM; Sapienza S; Waserman S; Du T; Olivenstein R; Wang NS; Martin JG
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 146, No. 1, pp. 163–169
Publisher
American Thoracic Society
Publication Date
July 1992
DOI
10.1164/ajrccm/146.1.163
ISSN
1073-449X