Journal article
Hemoglobin H (Hb H) disease in Canada: Molecular diagnosis and review of 116 cases
Abstract
Over the past decade, we have characterized at the DNA level a total of 116 hemoglobin H (Hb H) disease patients living in Canada. The majority of patients were of southeast Asian descent (Chinese, Filipino, Laotian, Vietnamese), with a small number being of Mediterranean, Middle Eastern or East Indian background. A total of 15 distinct genotypes were detected, all but one being compound heterozygotes for a two-gene cis deletion and a …
Authors
Waye JS; Eng B; Patterson M; Walker L; Carcao MD; Olivieri NF; Chui DHK
Journal
American Journal of Hematology, Vol. 68, No. 1, pp. 11–15
Publisher
Wiley
Publication Date
9 2001
DOI
10.1002/ajh.1142
ISSN
0361-8609