Journal article
Striatal dopamine metabolism in living monkeys examined by positron emission tomography
Abstract
Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This is the first time that the regional distribution of a neurotransmitter has been demonstrated in monkeys.
Authors
Garnett S; Firnau G; Nahmias C; Chirakal R
Journal
Brain Research, Vol. 280, No. 1, pp. 169–171
Publisher
Elsevier
Publication Date
November 1983
DOI
10.1016/0006-8993(83)91187-3
ISSN
0006-8993