Journal article
Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer
Abstract
High microvessel density, an indirect measure of angiogenesis, has been shown to correlate with increased tumour size, lymph node involvement and poor prognosis in non-small-cell lung cancer (NSCLC). Tumour cell vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell growth factor (PD-ECGF) expression correlate with angiogenesis and a poor outcome in this disease. In a retrospective study VEGF and PD-ECGF expression and …
Authors
O'Byrne KJ; Koukourakis MI; Giatromanolaki A; Cox G; Turley H; Steward WP; Gatter K; Harris AL
Journal
British Journal of Cancer, Vol. 82, No. 8, pp. 1427–1432
Publisher
Springer Nature
Publication Date
April 2000
DOI
10.1054/bjoc.1999.1129
ISSN
0007-0920
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdenocarcinomaAnalysis of VarianceCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellEndothelial Growth FactorsHumansImmunohistochemistryLung NeoplasmsLymphokinesMicrocirculationNeoplasm StagingNeovascularization, PathologicObserver VariationPrognosisProtein IsoformsSurvival AnalysisThymidine PhosphorylaseVascular Endothelial Growth Factor AVascular Endothelial Growth Factors