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Enhanced Rate of Nerve Regeneration and...
Journal article

Enhanced Rate of Nerve Regeneration and Directional Errors After Sciatic Nerve Injury in Receptor Protein Tyrosine Phosphatase ς Knock-Out Mice

Abstract

The receptor protein tyrosine phosphatase sigma (PTPsigma) is a member of the mammalian leukocyte common antigen-related (LAR) family. Its expression is developmentally regulated in neuronal tissues. The Drosophila homolog of the mammalian LAR family of phosphatases (DLAR) controls axon guidance during Drosophila embryogenesis. We have demonstrated previously that mice deficient in PTPsigma have CNS and peripheral nervous system abnormalities. …

Authors

McLean J; Batt J; Doering LC; Rotin D; Bain JR

Journal

Journal of Neuroscience, Vol. 22, No. 13, pp. 5481–5491

Publisher

Society for Neuroscience

Publication Date

July 1, 2002

DOI

10.1523/jneurosci.22-13-05481.2002

ISSN

0270-6474